The Ultimate Guide To ceesdekker
The Ultimate Guide To ceesdekker
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Utilizing single-molecule optical and AFM imaging and drive-spectroscopy tactics, we seek out to unravel the mechanistic elements of the construction and dynamics of chromosomes. Our study pursuits include things like:
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Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first ever study with the dynamics DNA supercoils and the discovery of supercoil hopping
Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quickly electron relay to redox enzymes and zeptomole protein-movie voltammetry
We condition microbes into varieties that deviate from their normal phenotype. Exclusively, I will display our ability to condition Dwell E. coli microorganisms into novel shapes such as rectangles, squares, triangles and circles.
Example (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim in the pore is highlighted in red, plus a 3D rendering of the movement of the DNA rod is shown.
The rotors harness Strength from a nanoscale h2o and ion stream which is created by a static chemical or electrochemical potential gradient from the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological ailments, suggesting approaches to developing Strength-transducing motors at nanoscale interfaces.
It was throughout this period that Dekker performed investigate on magnetic spin systems and on noise in superconductors and semiconductors.
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2008, first observation of protein-coated DNA translocation through nanopores; fixed the origin of your electrophoretic drive on DNA in nanopores; learned a big velocity raise of microtubules in electrical fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of noise in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA as a result of nanopores; 1st experimental research of ions conduction in nanofluidic channels; very first electrochemistry with individual solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initially electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of the mechanical Houses of double-stranded RNA; and initial one-molecule research of DNA translocation by a restriction-modification enzyme.